Fillet the catfish and wash the fillets, place fillets in a baking dish. Whisk together the milk and hot sauce and pour over the fillets. Cover the dish and place in the fridge for 8 hours, turning the fillets once at the 4 hour mark.

Mix the flours, corn meal, salt, peppers, and garlic powder in a shallow dish. Remove the fish from the fridge and let sit on the counter for 10 minutes to get them back to room temperature.

Heat the oil in a large thick skillet or pot, about 2 inches of oil is good. When the oil is hot, like deep frying type of hot, then it is ready. Remove the fillets from the milk and drain off any of the milk, roll the fillets in the corn meal and flour mixture, and deep dry for 2 minutes on each side or until golden brown, remove and place on a wire rack to drain. Serve.